Androgen dependency in acquired aplastic anemia.

Am J Med. 1977 Aug;63(2):320-4.

Androgen dependency in acquired aplastic anemia.

Azen EA, Shahidi NT.

We describe three patients with acquired aplastic anemia showing dependency on
androgens, with blood counts that correlated directly with variation in
oxymetholone dosage. In two of the patients, red cells, neutrophils and platelets
showed parallel fluctuations, whereas in one patient the red cells and white
cells, but not the platelets, fluctuated in relationship to oxymetholone therapy.
There was no hematologic response to dromostanolone in two patients. These
results support the benefit of androgen therapy in some patients with acquired
aplastic anemia.