Synchronous bilateral ductal carcinoma in situ of the male breast associated with gynecomastia in a 30-year-old patient following repeated injections of stanozolol.

Breast Cancer Res Treat. 2006 May;97(2):173-6. Epub 2005 Dec 3.

Erratum in:
    Breast Cancer Res Treat. 2006 May;97(2):177. Melcher, A [corrected to Melcher,
Gian A].

Synchronous bilateral ductal carcinoma in situ of the male breast associated with
gynecomastia in a 30-year-old patient following repeated injections of
stanozolol.

Staerkle RF, Lenzlinger PM, Suter SL, Varga Z, Melcher GA.

Department of Surgery, Spital Uster, Uster, Switzerland.

We report a rare case of synchronous bilateral and multifocal ductal carcinoma in
situ (DCIS) in a 30-year-old patient operated on for gynecomastia following
repeated injections of stanozolol, a non-aromatizable androgen. The familial
medical history was negative for breast cancer and work-up of serum hormone
levels was normal. The patient underwent a modified radical mastectomy without
axilla dissection 6 weeks following the primary procedure and recovered
uneventfully. The role of synthetic androgens in the development of male breast
neoplasia warrants further scrutiny.