J Tongji Med Univ. 1999;19(1):63-5.
Growth-promoting effect of recombinant human growth hormone and stanozolol in
girls with Turner syndrome.
Fang J, Ning C, Shu D, Wei H, Lin H, Wang M.
Department of Pediatrics, Tongji Hospital, Tongji Medical University, Wuhan
430030.
Ten girls with Turner syndrome were treated with a combination therapy of
recombinant human growth hormone (R-hGH) and low dose stanozolol for a period of
8 to 36 months. The results showed that when compared with the growth rate before
the treatment, the growth rates after treatment with R-hGH and stanozolol showed
a sustained increase, reaching 9.0 +/- 1.9 cm/year during the first year of
treatment; the height age increase by 2.5 +/- 0.8 years while the bone age
increase were 1.0 +/- 0.7 years; and the predicted final adult height at the end
of the first year of the treatment increased to 149.4 +/- 6.1 cm compared to
their original mean of 142.8 +/- 4.2 cm. We are led to conclude that therapy with
R-hGH in combination with stanozolol can increase the growth velocity and
significantly increase the predicted adult height of children with Turner
syndrome.
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