Am J Dermatopathol. 1987 Dec;9(6):515-9.
Effect of testosterone and anabolic steroids on the size of sebaceous glands in
power athletes.
Király CL, Collan Y, Alén M.
Department of Dermatology, South-Saimaa Central-Hospital, Lappeenranta, Finland.
The effect of testosterone and anabolic steroids on the size of sebaceous glands
was studied by means of interactive morphometry in skin biopsies of power
athletes. The subjects used self-administered high doses of testosterone and
anabolic steroids during a 4-week strength training period. After 4 weeks' use of
hormones, the area of sectioned sebaceous glands enlarged significantly by a
factor of 89.2% (p less than 0.005). The number of cells in the so-called
differentiating cell pool (DCP) and in the undifferentiated cell pool (UCP) also
increased significantly (p less than 0.025, p less than 0.05, respectively). The
size of the area occupied by UCP cells increased significantly (p less than
0.05). The study suggests that high doses of testosterone and anabolic steroids
lead to an enlargement of sebaceous glands in male power athletes.
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